文章基本信息

标题：حافظه کلامی، دیداری و در جریان در بیماران مبتلا به ‌اسکیزوفرنیا و بستگان درجه‌ اول
其他标题：Verbal Memory, Visual Memory and Working Memory in Patients with Schizophrenia and their First-degree Relatives
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作者：Shahrzad Mazhari ; Hasan Haghshenas ; Ali Firooz-abadi 等
期刊名称：Iranian Journal of Psychiatry and Clinical Psychology
印刷版ISSN：1735-4315
电子版ISSN：2228-7515
出版年度：2007
卷号：12
期号：4
页码：359-364
语种：English
出版社：Tehran University of Medical Sciences
其他摘要：Abstract Objectives: Assessment of cognitive deficits in patients with schizo-phrenia bears significant implications, particulary in localizing the underlying accompanying neurological impairments. This study aimed for evaluation of cognitive deficits in first-degree relatives of these patients who reflect the same underlying genetic vulnerability for the disorder. Method: In this cross-sectional study, 30 patients with schizophrenia, 30 first-degree relatives, and 30 control subjects were assessed. They completed tests of verbal & visual paired associate recall, Wechsler digit span, and Paced Auditory Serial Addition Test (PASAT). Data were analysed using statistical t-test, ANOVA, Tukey test, Chi-square, and Kruskal-Wallis test. Results: Our study revealed alterations in the memory of patients with schizophrenia and their first-degree relatives compared to the controls. Both patients and their relatives also showed significant diffrence in verbal and visual paired associate recall tests, backward digit span, and PASAT. Conclusion: Diminished cognitive functions is observed in first-degree relatives of patients with schizophrenia. Verbal and visual paired asso-ciation tests, Backward digit Span test, and PASAT may indicate vulner-ability towards this disorder.
关键词：کلیدواژه: اسکیزوفرنیا; بستگان درجه‌ اول; حافظه کلامی‌; حافظه دیداری; حافظه در جریان
其他关键词：Key words: Schizophrenia; first-degree relatives; verbal memory; visual memory; working memory