文章基本信息

标题：PROSTATE-SPECIFIC ANTIGEN (PSA) DENSITY AND FREE TO TOTAL PSA RATIO IN DIAGNOSING PROSTATE CANCER WITH PROSTATE-SPECIFIC ANTIGEN LEVELS OF 4.0 NG/ML OR LESS
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作者：LIU XIN ; TANG JIE ; FEI XIANG 等
期刊名称：Iranian Journal of Public Health
印刷版ISSN：2251-6085
电子版ISSN：2251-6093
出版年度：2015
卷号：44
期号：11
页码：1466-1472
语种：English
出版社：Tehran University of Medical Sciences
摘要：Background: We aimed to value the usefulness of free to total prostate-specific antigen and Prostate-specific antigen (PSA) density for prostate cancer in the patients with PSA levels of 4.0 ng/ml or less.
Methods: A total of 343 subjects with PSA levels of 4.0 ng/ml or less were biopsied. All patients were divided into four groups according to the PSA levels: 0 to 1.0 ng/ml, 1.1 to 2.0 ng/ml, 2.1 to 3.0 ng/ml, and 3.1 to 4.0 ng/ml. The reliability of cancer detection in relation to the f/t PSA ratio and PSAD were estimated.
Results: Overall, 65 people were diagnosed with prostate cancer. The detection rate was 16.28% ? 17.17%, 21.82%, 25.00% in subjects with PSA levels of 0 to 1.0 ng/ml, 1.1 to 2.0 ng/ml, 2.1 to 3.0 ng/ml, and 3.1 to 4.0 ng/ml, respec-tively. The f/t PSA ratio was significantly lower in patients with prostate cancer and PSA levels of 2.1 to 4.0 ng/ml (P<0.05). The PSAD had no statistical significance between the two groups.
Conclusions: Routine prostate biopsy should be undertaken if the f/t PSA ratio less than 15% with /without abnor-mal DRE/TRUS findings.
关键词：BIOPSY; PROSTATE CANCER; PROSTATE-SPECIFIC ANTIGEN; PSA RATIO; PSAD