Epidural abscess is a rare complication of epidural catheterization. Moreover, the early diagnosis of abscess may be difficult because of nonspecific symptoms and underlying painful disorder. It's outcome is strongly associated with the level of neurologic function at the time of diagnosis. We report the case of a cancer patient with diabetes mellitus, who developed an epidural abscess after 90 days of continuous epidural catheterization. In this case, the patient had no other neurologic symptom except for a tingling sensation in both legs, which recovered fully after surgery. This case demonstrates that the early diagnosis of epidural abscess and prompt surgical procedures are important, and can result in a good neurologic outcome.