文章基本信息

标题：Immunological parameters as a new lead in the diagnosis of ovarian cancer
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作者：T. BAERT ; D. TIMMERMAN ; I. VERGOTE 等
期刊名称：Facts, Views & Vision in ObGyn
印刷版ISSN：2032-0418
出版年度：2015
卷号：7
期号：1
页码：67-72
出版社：Universa Press
摘要：Ovarian cancer is the leading cause of pelvic gynecological cancer death in Europe. Prognosis is poor in women diagnosed at stage III to IV or in case disease recurs. Platin-based chemotherapy and radical surgery have already improved prognosis significantly. Novel strategies in the treatment of ovarian cancer are being searched for. The study of the immune system as a valuable parameter in the development of ovarian cancer has been neglected for a long time. Nevertheless, this is a field in full progression and might open new perspectives in the diagnosis and prognosis of ovarian cancer patients and could lead to a more motivated choice of targeted therapies.
关键词：Ovarian cancer; diagnosis; prognostic marker; immunosuppression; regulatory T cell; myeloid derived;suppressor cells; tumor-associated macrophages.