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文章基本信息

  • 标题:The relationship between obesity, pregnancy, and levels of indoleamine 2,3-dioxygenase
  • 本地全文:下载
  • 作者:Tyler, Eric M ; Santillan, Donna A. ; Scroggins, Sabrina M.
  • 期刊名称:Proceedings in Obstetrics and Gynecology
  • 印刷版ISSN:2154-4751
  • 出版年度:2016
  • 卷号:5
  • 期号:3
  • 页码:1-2
  • 出版社:University of Iowa
  • 摘要:For a successful pregnancy to occur, foreign genetic material such as the allogeneic fetus must be tolerated within the maternal host. Indoleamine 2,3-dioxygenase (IDO) is an enzyme induced by pro-inflammatory cytokines that has been shown to be key to this process. Obesity as a pro-inflammatory state is associated with poor obstetric outcomes. The primary objective of this study is to investigate the relationship between obesity and IDO activity.
  • 关键词:Preeclampsia; obesity in pregnancy; immunology of pregnancy; fetal tolerance
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