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标题：Late preterm infants – impact of perinatal factors on neonatal results. A clinical study
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作者：Grzegorz Jakiel ; Maria Wilińska ; Małgorzata Bińkowska 等
期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2015
卷号：22
期号：3
页码：536-541
DOI：10.5604/12321966.1167730
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction. Infants born between the 34th – 36th week of pregnancy account for 75% of all preterm infants. Their seeminglyslight immaturity is related to serious health problems.Objective. The aim of the study was to analyse perinatal factors that influence the occurrence in infants of such problemsas respiratory failure, metabolic problems and early onset sepsis (EOS).Materials and method. The material for the study included all mothers and their late preterm infants: 34+0 – 36+6 bornin our hospital (a tertiary referral academic centre) in 2010 and 2011. The course of pregnancy and delivery, the type ofdelivery, applied preventive measures and treatment, as well as demographic data and the clinical state of infants were allanalysed. Data from individual documentation of each mother and infant were collected by 5 designated people and datareliability was independently monitored by a random control of the documentation conducted by the supervising person.Results. A statistically significant relationship between the occurrence of respiratory distress syndrome and infant immaturity,bad state after birth and sepsis in infants were confirmed. Sepsis was more common in the case of vaginal delivery, andcoexisted with respiratory distress syndrome. The mother’s diseases during pregnancy, a perinatal preventive antibiotictherapy, and possible delivery complications did not influence the infection. Perinatal asphyxia in an infant positivelycorrelated with a Caesarean section and respiratory distress syndrome after birth.Conclusions. It is necessary to thoroughly establish the type of delivery of a late preterm infant in order to prevent aninfection in the newborn child. The improvement of diagnosis of intrauterine hypoxia may reduce the number of Caesareansections. The decision about late preterm delivery should be based on indices of the mother’s state of health. Prematuredelivery is related to the occurrence of respiratory distress syndrome in a late preterm infant, although the risk is reducedby the application of an antenatal steroid therapy.
关键词：late preterm; perinatal risk factors; respiratory distress syndrome; infection; intrauterine asphyxia