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标题：Clinical relevance of Corylus pollen in Poznań, western Poland
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作者：Łukasz Grewling ; Dorota Jenerowicz ; Małgorzata Nowak 等
期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2014
卷号：21
期号：1
页码：64-69
出版社：Institute of Agricultural Medicine in Lublin
摘要：Background. In Central Europe, hazel (Corylus sp.) pollen is considered to be an important aeroallergen in early spring.Objective. This study examines hazel pollen levels in Poznań, western Poland, and the clinical relevance of this aeroallergenin the city.Methods. Corylus pollen data (1996–2010) were obtained by volumetric spore trap located near the centre of Poznań.Clinical data (2006–2010), i.e. skin prick test (SPT) and allergen-specific IgE measurements (asIgE), were supplied by theAllergy Diseases Diagnostic Centre in Poznań.Results. Mean diurnal hazel pollen concentrations peaked around 14:00–16:00 when mean bi-hourly pollen concentrationswere ~60 P m-3. Onset of the hazel pollen season varied up to 87 days annually, and was significantly (r=–0.647; p<0.01)related to mean maximum temperature during late December. SPT data revealed that ~11% of allergy patients had positiveskin reactions to Corylus pollen allergens, and most of these (94.4%) reacted to pollen allergens from other members ofthe Betulaceae family – alder or birch. Of those sensitized, 53% suffered from atopic dermatitis. Of patients examined forserum asIgE, 26.0% had asIgE measurements in classes 5 and 6.Conclusions. Hazel pollen has a detrimental effect on the allergic population of Poznań, with more than half of thosesensitised to hazel pollen allergens showing symptoms of atopic dermatitis. Hazel pollen concentrations reach levelsrecognized as being able to induce allergy symptoms, especially in the afternoon and early evening when many peopleare returning home from work. The cross-reactivity with other members of the Fagales order also increases the allergenicpotential of hazel pollen.
关键词：asIgE; hazel; atopic dermatitis; sensitization rates; skin-prick test; RAST; cross-reactivity; Betulaceae