The prevalence of computers in the classroom is compelling teachers to develop new instructional skills. This paper provides a theoretical perspective on an innovative pedagogical approach to science teaching that takes advantage of technology to create a connected classroom. In the connected classroom, students collaborate and share ideas in multiple ways producing a record of work that is persistent and accessible via networked-based computing (i.e., “the cloud”). The instruction method, called Computer Supported Collaborative Science (CSCS), uses web-based resources to engage all learners in the collection, analysis, and collaborative interpretation of classroom data that turns hands-on classroom activities into authentic scientific experiences. This paper describes CSCS and how it corresponds to key parts of the Next Generation Science Standards.