文章基本信息

标题：The re-emergence of pertussis: implications for diagnosis and surveillance
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作者：Vitali Sintchenko
期刊名称：New South Wales Public Health Bulletin
印刷版ISSN：1034-7674
电子版ISSN：1834-8610
出版年度：2008
卷号：19
期号：7&8
页码：143-145
DOI：10.1071/NB07005
出版社：CSIRO Publishing
摘要：Pertussis, or whooping cough, a highly contagious disease caused by Bordetella pertussis, is making a comeback globally and nationally in spite of reasonable vaccination coverage. This paper provides an update on laboratory testing methods that assist the confirmation of clinical disease and investigation of outbreaks. Laboratory confirmation of the diagnosis by polymerase chain reaction or serology should be attempted, especially when atypical pertussis is suspected clinically. Genetic and antigenic variations in virulence factors of strains circulating in the population should also be monitored.