文章基本信息

标题：miR-181 suppresses metastasis via MMP-14
本地全文：下载
作者：Eric Roth ; Jian Cao
期刊名称：Aging
出版年度：2015
卷号：7
期号：10
页码：740-741
出版社：U.S.Department of Health & Human Service
摘要：Metastasis accounts for 90% of all cancer-related deaths. Much effort has been made to identify key molecules controlling metastasis. However, due to the complicated wiring of the cancer signaling networks, key players initiating cancer metastasis have not been defined. This situation has thwarted target-based drug discovery aimed at preventing cancer metastasis. Regardless of which molecules initiate tumor, cancer cells must be equipped with proteases for invasive behavior [1].
关键词：cancer; metastasis; Matrix; Metalloproteinase ; miRNA.