文章基本信息

标题：Synergy of cancer immunotherapy and radiotherapy
本地全文：下载
作者：Aaron S. Mansfield ; Sean S. Park ; Haidong Dong 等
期刊名称：Aging
出版年度：2015
卷号：7
期号：3
页码：144-145
出版社：U.S.Department of Health & Human Service
摘要：Radiotherapy is a cornerstone of cancer care in non- metastatic patients. It has been incorporated into the treatment regimens of major tumor histologies with curative intent, and is broadly applied for almost any tumor type in the metastastic setting to alleviate symptoms. The cytotoxic effects of radiotherapy have primarily been attributed to double strand DNA damage; however, recent evidence suggests that its immunomodulatory effects can contribute to its therapeutic efficacy. This synergistic potential from combining radiotherapy and immunotherapy may have a role in patients with locally advanced or metastatic cancer.