文章基本信息

标题：Morphological Manifestations of the Dandy-Walker Syndrome in Female Members of a Family
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作者：Titlić, Marina ; Alfirević, Stanko ; Kolić, Krešimir 等
期刊名称：Collegium Antropologicum
印刷版ISSN：0350-6134
出版年度：2015
卷号：39
期号：1
页码：225-228
语种：English
出版社：Hrvatsko antropološko društvo
摘要：The Dandy-Walker syndrome (DWS) is a hereditary disorder, appearing somewhat more frequently in women. The most important characteristics of the DWS are the lack of the cerebellar vermis, varying from a partial lack to a complete agenesis, and enlargement of the cerebrospinal spaces, especially in the fourth ventricle. The above mentioned morphological changes clinically manifest in ataxia, increased intracranial pressure and hydrocephalus. Here is presented a family with DWS, where the disease is contracted only by female members, in two generations, whereas no signs of DWS have been noticed in male family members. DWS is clinically manifested from early childhood to middle age, with the morphological changes varying from hypoplastic cerebellar vermis to widening of the brain ventricles and hydrocephalus and arachnoid cyst in the occipital part.
关键词：Dandy-Walker; malformation; brain; women