文章基本信息

标题：Iron Metabolism Dysregulation and Cognitive Dysfunction in Pediatric Obesity: Is There a Connection?
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作者：Anna Grandone ; Pierluigi Marzuillo
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2015
卷号：7
期号：11
页码：9163-9170
DOI：10.3390/nu7115458
语种：English
出版社：MDPI Publishing
摘要：Obesity and iron deficiency (ID) are two of the most common nutritional disorders in the world. In children both conditions deserve particular attention. Several studies revealed an association between obesity and iron deficiency in children and, in some cases, a reduced response to oral supplementation. The connecting mechanism, however, is not completely known. This review is focused on: (1) iron deficiency in obese children and the role of hepcidin in the connection between body fat and poor iron status; (2) iron status and consequences on health, in particular on cognitive function; (3) cognitive function and obesity; (4) suggestion of a possible link between cognitive dysfunction and ID in pediatric obesity; and implications for therapy and future research.
关键词：obesity; iron deficiency; cognitive dysfunction; hepcidin; children obesity ; iron deficiency ; cognitive dysfunction ; hepcidin ; children