文章基本信息

标题：Acquired cystic disease and renal cell carcinoma in hemodialysis patients: A case report on three patients
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作者：Mijušković, Mirjana ; Milović, Novak ; Kovačević, Božidar 等
期刊名称：Vojnosanitetski pregled
印刷版ISSN：0042-8450
出版年度：2015
卷号：72
期号：10
页码：932-936
DOI：10.2298/VSP140311027M
出版社：Military Medical Academy, INI
摘要：Introduction. Renal cell carcinoma (RCC) is derived from renal tubular epithelial cells and represents approximately 3.8% of all malignancies in adults. The incidence of renal cell carcinoma has been growing steadily and ranging from 0.6 to 14.7 for every 100,000 inhabitants. Patients with end-stage renal disease and acquired cystic kidney disease are at increased risk of developing RCC while undergoing dialysis treatment or after renal transplantation. Case report. We presented 3 patients undergoing hemodialysis, with acquired cystic kidney disease accompanied by the development of RCC. In all the patients tumor was asymptomatic and discovered through ultrasound screening in 2 patients and in 1 of the patients by post-surgery pathohistological analysis of the tissue of the kidney excised using nephrectomy. All the three patients had organ-limited disease at the time of the diagnosis and they did not require additional therapy after surgical treatment. During the follow- up after nephrectomy from 6 months to 7 years, local recurrence or metastasis of RCC were not diagnosed. Conclusion. Acquired cystic kidney disease represents a predisposing factor for the development of renal cell carcinoma in dialysis patients and requires regular ultrasound examinations of the abdomen aimed at early diagnosis of malignancies. Prognosis for patients with endstage renal disease and RCC is mostly good because these tumors are usually of indolent course.
关键词：renal dialysis; kidney diseases; cystic; hemodyalisis; nephrectomy; treatment outcome