文章基本信息

标题：Experimental investigation of bone mineral density in Thoroughbreds using quantitative computed tomography
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作者：Kazutaka YAMADA ; Fumio SATO ; Tohru HIGUCHI 等
期刊名称：Journal of Equine Science
印刷版ISSN：1340-3516
电子版ISSN：1347-7501
出版年度：2015
卷号：26
期号：3
页码：81-87
DOI：10.1294/jes.26.81
出版社：Japanese Society of Equine Science
摘要：Bone mineral density (BMD) is one of the indications of the strength and health. BMD measured by quantitative computed tomography (QCT) was compared with that measured by dual energy X-ray absorptiometry (DXA) and radiographic bone aluminum equivalence (RBAE). Limbs were removed from horses that had been euthanized for reasons not associated with this study. Sixteen limbs (left and right metacarpals and metatarsals) from 4 horses were used to compare BMD as measured by QCT with those measured by DXA and RBAE. There was a strong correlation between BMD values measured by QCT and those measured by DXA (R²=0.85); correlation was also observed between values obtained by QCT and those obtained by RBAE (R²=0.61). To investigate changes in BMD with age, 37 right metacarpal bones, including 7 from horses euthanized because of fracture were examined by QCT. The BMD value of samples from horses dramatically increased until 2 years of age and then plateaued, a pattern similar to the growth curve. The BMD values of bone samples from horses euthanized because of fracture were within the population range, and samples of morbid fracture were not included. The relationship between BMD and age provides a reference for further quantitative studies of bone development and remodeling. Quantitative measurement of BMD using QCT may have great potential for the evaluation of bone biology for breeding and rearing management.
关键词：bone mineral density;dual energy X-ray absorptiometry;quantitative computed tomography;radiographic bone aluminum equivalence;Thoroughbred