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标题：Growth Performance, Fasting Plasma Glucose and Lipid Profile of Sprague-Dawley Rats Fed Different Levels of Omani Halwa
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作者：Amanat Ali ; Khalid M. Al-Zuhaibi ; Mostafa I. Waly 等
期刊名称：Pakistan Journal of Nutrition
印刷版ISSN：1680-5194
电子版ISSN：1994-7984
出版年度：2015
卷号：14
期号：8
页码：503-510
DOI：10.3923/pjn.2015.503.510
出版社：Asian Network for Scientific Information
摘要：Omani halwa is a traditional sweet delicacy. The present study evaluated the effects of feeding different levels of Omani halwa on the growth performance, fasting plasma glucose , glycated hemoglobin (HbA1c) and plasma lipid profile of Sprague-Dawley rats. Forty two, 4 weeks old male SD-rats were randomly divided into 7 groups containing 6 rats in each. Six experimental diets, (in which the normal rat chow was replaced with either white or black Omani halwa at 10, 15 and 20% level), were prepared and fed for 10 weeks. The group fed on rat chow acted as control. No significant (p<0.05) differences were observed in the feed consumption and growth performance of rats fed diets containing different levels and types of halwa. Significant (p<0.05) differences were observed in fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) values in rats fed different experimental diets. Diets containing 20% of halwa showed significantly (p<0.05) higher FPG and HbA1c values. Similarly the rats fed diets containing 20% of halwa showed significantly (p<0.05) higher lipid profile i.e., TC, TG, HDL-C and LDL-C values as compared to control. However, the TC/HDL-C ratio did not differ significantly (p>0.05). The plasma creatinine levels differed significantly (p<0.05) whereas the plasma albumin levels did not differ (p>0.05) in rats fed various experimental diets. Feeding Omani halwa at 15% level in diets did not affect (p>0.05) the growth, fasting plasma glucose , glycated hemoglobin (HbA1c) and lipid profile of rats.