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标题：Cardiovascular Risks and Sympathovagal Imbalance In Polycystic Ovarian Syndrome
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作者：K. Saranya*, G. K. Pal*, S. Habeebullah** Pravati Pal
期刊名称：International Journal of Basic & Applied Physiology
印刷版ISSN：2320-172X
出版年度：2012
期号：1451
页码：192-201
出版社：Society of Basic & Applied Physiology
摘要：Polycystic ovary syndrome (PCOS), the commonest cause of infertility, is a heterogeneous syndrome with a significant alteration in autonomic modulation in the form of increased adrenergic drive and a depressed vagal activity. The various co-morbidities associated with PCOS such as obesity, insulin resistance, dyslipidemia, hyperandrogenism and altered thyroid profile, are known to cause significant alteration in autonomic dysfunctions. Assessment of autonomic functions has proved to be a sensitive tool in diagnosing the early features of CV dysfunction in PCOS. When detected early, it enables an early intervention to yield a better cardiovascular health to these patients. The simplest approach of restoring the sympathovagal balance would be the life style modifications in the form of regular exercise and practice of yoga. Regular exercise decreases adiposity and improves the sensitivity of insulin in the peripheral tissues and yoga improves general cardiovascular health. Thus, these alternative therapies can supplement the medical therapy advocated to these patients and would lead to better outcome in both reproductive and cardiovascular health. Key words: Cardiovascular dysfunctions, sympathovagal imbalance, PCOS