文章基本信息

标题：PREVALENCE OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DIARRHEA IN HOSPITALIZED PATIENTS WITH NOSOCOMIAL DIARRHEA
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作者：SADEGHIFARD NOUR KHODA ; SALARI M.H. ; GHASSEMI M.R. 等
期刊名称：Iranian Journal of Public Health
印刷版ISSN：2251-6085
电子版ISSN：2251-6093
出版年度：2005
卷号：34
期号：4
页码：67-72
语种：English
出版社：Tehran University of Medical Sciences
摘要：Clostridium difficile is a frequently identified cause of nosocomial gastrointestinal disease. It has been proved to be a causative agent in antibiotic-associated diarrhea, antibiotic-associated colitis, and pseudomembraneous colitis. This study was aimed to determine the prevalence of C.difficile- associated diarrhea in hospitalized patients with nosocomial diarrhea. The 942 hospitalized patients stool samples with nosocomial diarrhea were collected at three hospitals in Tehran from Dec 2002 to Feb 2004.All the stool samples were cultured and in 97 (prevalence: 10.9%) samples grew C.difficile that 57 (prevalence: 6.1%) isolates were toxigenic by cytotoxicity assay and so 57 patients had C.difficile- associated diarrhea. Results of statistical analysis showed significant difference between the rate of C.difficile associated diarrhea and the patients ages (P<0.05).
关键词：TOXIGENIC CLOSTRIDIUM DIFFICILE; ANTIBIOTIC-ASSOCIATED DIARRHEA; NOSOCOMIAL DIARRHEA; CYTOTOXICITY ASSAY; IRAN