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标题：PREVALENCE OF HEPATITIS G VIRUS (HGV) IN HIGH-RISK GROUPS AND BLOOD DONORS IN TEHRAN, IRAN
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作者：AMINI SAFIEH ; ANDALIBI MAHMOODABADI S. ; LAMIAN S. 等
期刊名称：Iranian Journal of Public Health
印刷版ISSN：2251-6085
电子版ISSN：2251-6093
出版年度：2005
卷号：34
期号：4
页码：41-46
语种：English
出版社：Tehran University of Medical Sciences
摘要：The hepatitis G virus (HGV) is a newly discovered RNA virus, which is associated with acute or chronic hepatitis. A survey was conducted in thalassemic patients, intravenous drug users (IVDU) and blood donors aiming to investigate the prevalence of hepatitis G virus (HGV) infection in these groups in Tehran. The presence of HGV RNA in these populations was determined using reverse transcriptase polymerase chain reaction (RT-PCR) of the 5’ non-coding region (NCR) of the virus. One percent of blood donors, 12.9% of thalassemics and 8.8% of the IVDUs, were infected with HGV. Twenty-five percent of HGV positive cases were also positive for HCV and none were positive for HBV-DNA. The greatest proportion of HCV positive cases were seen in IVDU group (67.4%) being the only HIV positive group (8.8%). In conclusion our study showed that HGV infection occurs with relatively intermediate frequency among thalassemics and IVDUs in Iran and a higher rate of HGV-RNA was observed in older IVDUs.
关键词：GB VIRUS C; BLOOD DONOR; IVDU; THALASSEMIA; HGV; IRAN