文章基本信息

标题：Magnesium in Prevention and Therapy
本地全文：下载
作者：Uwe Gröber ; Joachim Schmidt
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2015
卷号：7
期号：9
页码：8199-8226
DOI：10.3390/nu7095388
语种：English
出版社：MDPI Publishing
摘要：Magnesium is the fourth most abundant mineral in the body. It has been recognized as a cofactor for more than 300 enzymatic reactions, where it is crucial for adenosine triphosphate (ATP) metabolism. Magnesium is required for DNA and RNA synthesis, reproduction, and protein synthesis. Moreover, magnesium is essential for the regulation of muscular contraction, blood pressure, insulin metabolism, cardiac excitability, vasomotor tone, nerve transmission and neuromuscular conduction. Imbalances in magnesium status—primarily hypomagnesemia as it is seen more common than hypermagnesemia—might result in unwanted neuromuscular, cardiac or nervous disorders. Based on magnesium’s many functions within the human body, it plays an important role in prevention and treatment of many diseases. Low levels of magnesium have been associated with a number of chronic diseases, such as Alzheimer’s disease, insulin resistance and type-2 diabetes mellitus, hypertension, cardiovascular disease (e.g., stroke), migraine headaches, and attention deficit hyperactivity disorder (ADHD).
关键词：magnesium; hypomagnesemia; cardiovascular disease; diabetes mellitus; asthma; ADHD; Alzheimer’s disease magnesium ; hypomagnesemia ; cardiovascular disease ; diabetes mellitus ; asthma ; ADHD ; Alzheimer’s disease