文章基本信息

标题：Selective chemical binding enhances cesium tolerance in plants through inhibition of cesium uptake
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作者：Eri Adams ; Vitaly Chaban ; Himanshu Khandelia 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2015
卷号：5
DOI：10.1038/srep08842
出版社：Springer Nature
摘要：High concentrations of cesium (Cs⁺) inhibit plant growth but the detailed mechanisms of Cs⁺ uptake, transport and response in plants are not well known. In order to identify small molecules with a capacity to enhance plant tolerance to Cs⁺, chemical library screening was performed using Arabidopsis . Of 10,000 chemicals tested, five compounds were confirmed as Cs⁺ tolerance enhancers. Further investigation and quantum mechanical modelling revealed that one of these compounds reduced Cs⁺ concentrations in plants and that the imidazole moiety of this compound bound specifically to Cs⁺. Analysis of the analogous compounds indicated that the structure of the identified compound is important for the effect to be conferred. Taken together, Cs⁺ tolerance enhancer isolated here renders plants tolerant to Cs⁺ by inhibiting Cs⁺ entry into roots via specific binding to the ion thus, for instance, providing a basis for phytostabilisation of radiocesium-contaminated farmland.