文章基本信息

标题：Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells
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作者：Allison Suarez ; Tasuku Ueno ; Robert Huebner 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2014
卷号：4
DOI：10.1038/srep04693
出版社：Springer Nature
摘要：We provide direct evidence that Bin/Amphiphysin/Rvs (BAR) family members bend the steady state membrane architecture of organelles in intact cells. In response to inducible BAR molecular actuators, organelles exhibit distinct changes to the orientation and degree of their membrane curvature. This rapidly inducible system may offer a mechanism by which to better understand the structure-function relationship of intracellular organelles.