文章基本信息

标题：High-risk HPV nucleic acid detection kit–the careHPV test –a new detection method for screening
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作者：Hong Ying ; Fang Jing ; Zhao Fanghui 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2014
卷号：4
DOI：10.1038/srep04704
出版社：Springer Nature
摘要：This study assessed the clinical accuracy of the correlation between the care HPV test and the HC2 test, as well as the correlation between the care HPV test and the HPV-PCR test. From September 21 to December 31, 2009, 419 cervical specimens from women, 30–49 years, were collected. All women were assessed by Digene HC2 High-Risk HPV DNA Test (HC2), care HPV test, and HPV-PCR. The concordance rate between care HPV and HC2 was 93.81% and between care HPV and HPV-PCR 88.12%. The sensitivity and specificity of the care HPV test to detect cancers of equal or greater severity than CIN 2 were 85.71% and 83.15% respectively. Results from care HPV, HC2, and HPV-PCR were highly consistent. The care HPV test has good sensitivity and specificity for the detection of HPV infection and is a promising primary screening method for cervical cancer in low-resource regions.