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  • 标题:Characterization of a β-L-Arabinopyranosidase from Bifidobacterium longum subsp. longum
  • 本地全文:下载
  • 作者:Michiko Shimokawa ; Kanefumi Kitahara ; Kiyotaka Fujita
  • 期刊名称:Journal of Applied Glycoscience
  • 印刷版ISSN:1344-7882
  • 电子版ISSN:1880-7291
  • 出版年度:2015
  • 卷号:62
  • 期号:1
  • 页码:1-6
  • DOI:10.5458/jag.jag.JAG-2014_006
  • 出版社:The Japanese Society of Applied Glycoscience
  • 摘要:

    We characterized a β-L-arabinopyranosidase AbpBL (BLLJ_1823) belonging to the glycoside hydrolase family 27 (GH27) from Bifidobacterium longum subsp. longum JCM1217. The recombinant AbpBL expressed in Escherichia coli hydrolyzed p NP-β-L-arabinopyranoside but not p NP-α-D-galactopyranoside. The enzyme also liberated L-arabinose from the β-L-arabinopyranosyl side chain of larch wood arabinogalactan. However, we could not detect any β-L-arabinopyranosidase activity or remarkable transcriptional induction in cultured cells of B. longum subsp. longum . Mutagenesis experiments revealed that I56D and I56A mutants both exhibited β-L-arabinopyranosidase and α-D-galactopyranosidase activities. AbpBL Ile-56 residue is a critical residue for the specificity of β-L-arabinopyranosidase.

  • 关键词:β-L-arabinopyranosidase; α-D-galactopyranosidase; type II arabinogalactan; Bifidobacterium longum subsp. longum ; glycoside hydrolase family 27
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