文章基本信息

标题：Endogenous Neuroprotective Molecules and Their Mechanisms in the Central Nervous System
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作者：Hideki Hayashi ; Norio Takagi
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2015
卷号：38
期号：8
页码：1104-1108
DOI：10.1248/bpb.b15-00361
出版社：The Pharmaceutical Society of Japan
摘要：Functions of the central nervous system (CNS) are based on a complex neural network. It is believed that the CNS has several neuroprotective mechanisms operated by neurons, glia and other types of cells against various types of neuronal damage. Since mature, differentiated neurons are not able to divide, it is important to protect neurons from damage prior to death. The neuroprotective effects of a number of pharmaceutical agents and natural products against necrosis and apoptosis of the CNS neurons have been reported, thus this review will mainly discuss several endogenous neuroprotectants and their mechanisms.