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  • 标题:Mild cognitive deficits in cancer: their clinical assessment and management
  • 作者:Bénédicte Giffard ; Marie Lange ; Isabelle Léger
  • 期刊名称:Revue de Neuropsychologie Neurosciences Cognitives et Cliniques
  • 印刷版ISSN:2101-6739
  • 电子版ISSN:2102-6025
  • 出版年度:2015
  • 卷号:7
  • 期号:2
  • 页码:127-134
  • DOI:10.1684/nrp.2015.0344
  • 出版社:John Libbey Eurotext
  • 摘要:Figures Tables Authors Bénédicte Giffard 1 2 3 4 * Marie Lange 5 6 Isabelle Léger 5 7 1 INSERM, U1077, Caen, France 2 Normandie Université, UMR-S1077, UFR de psychologie, Esplanade de la Paix, 14032 Caen cedex, France 3 École Pratique des Hautes Études, UMR-S1077, Caen, France 4 CHU de Caen, U1077, Caen, France 5 Inserm, U1086, Caen, France 6 Service de recherche clinique, Centre François Baclesse, Caen, France 7 Gustave Roussy, Villejuif, France * Correspondance Key words: Cancer, cognition, neuropsychology DOI : 10.1684/nrp.2015.0344 Page(s) : 127-34 Published in: 2015 Cognitive functioning in cancer represents a new field of research, and many studies report mild cognitive deficits during and after completing adjuvant chemotherapy, often referred to as “chemobrain”. Some prospective studies report cognitive deficits even though adjuvant therapy has not yet begun, suggesting that, in addition to aggressive effect of chemotherapy, other factors, such as biological and psychological factors, also play a negative role on cognition in cancer. Although subtle, these cognitive dysfunction may impact the quality of life as well as compliance to treatment, and assessing cognitive impairment in the cancer population is a challenge in clinical practice. Improving the quality of life during and after a cancer has become a public health priority. In clinical practice, the cognitive complaint of patients must be taken into account in order to improve their quality of life and to propose supportive measures. In this way, a neuropsychological assessment adapted to these mild cognitive deficits and involving an assessment of possible psychopathological impairment is essential. This paper presents a summary of the cognitive impairments related to cancer and its treatments, including chemotherapy, and of the methodology used in the literature to detect these deficits. We propose recommendations for a neuropsychological assessment applicable to the clinical practice in France, and some elements of management.
  • 关键词:Cancer; cognition; neuropsychology
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