文章基本信息

标题：生物組織に於けるビタミンCの生成に就て (第II報)
本地全文：下载
作者：白神敬子 ; 板倉幸枝 ; 小川政禧等
期刊名称：日本栄養・食糧学会誌
印刷版ISSN：0287-3516
电子版ISSN：1883-2849
出版年度：1958
卷号：11
期号：3
页码：145-148
DOI：10.4327/jsnfs1949.11.145
出版社：Japanese Society of Nutrition and Food Science
摘要：1) In the lumen of rat small intestine, D-glucurono lactone was converted to l -ascorbic acid, and this was promoted by the presence of SH compounds, such as glutathionine (GSH) or cysteine, but inhibited by P -chloromercuri benzoate (PCMB), NaAsO₂, or CH, ICOOH. 2) In the case of ascorbic acid formation from d -glucose, Robinson-ester, or Harden Young-ester neither of SH compounds nor their inhibitors were observed to have this effect. 3) Yet the biosynthesis of l -ascorbic acid from Cori-ester was conspicuously accelerated by oxidized glutathione (GSSG) or PCMB, and inhibited by GSH and cysteine. 4) These results suggest us that the phosphorylation of D-glucose to Cori-ester is the first and direct pathway of the biosynthesis of l -ascorbic acid from D-glucose in intestine.