In the last two papers, the author proposed a new decision process of design values related to wave-induced responses. The process is composed of the two stages, namely, the selection of most severe sailing conditions and the estimation of short-term responses including non-linear effects in the selected conditions. The author considers that the preparation studies were finished by the last two papers. The present paper demonstrates the effectiveness of the new process taking the large container ship for which full-scale measurements were carried out in the North Pacific Ocean in winter, as a practical example. In view of bending strength and deck wetness from the bow, most severe sailing conditions are selected and non-linear simulations are carried out around them. The results seem to be reasonable, when compared with the results of the full-scale measurements and the previous study on non-linear responses of a ship with large bow flare.