摘要:The protozoan parasite Entamoeba histolytica is a causative agent of human amebiasis. Recent molecular studies have shown genetic diversity among E. histolytica isolates, thus indicating the usefulness of isolate identification at the genotype level in understanding the molecular epidemiology of amebic infection. In the present study, we identified the genotypes of seven isolates from patients in Osaka City by sequence analysis of polymorphic loci. The genotypes of the isolates examined were varied at every locus. The five isolates showed novel combinations of genotypes quite different from those of the isolates reported previously, and therefore appeared to be novel types peculiar to Osaka City. This is the first report on the genetic characterization of E. histolytica isolates in Osaka City.
关键词:Entamoeba histolytica;genetic polymorphism;genotype;Osaka City