文章基本信息

标题：Effects of Hair Dyeing on DNA Damage in Human Lymphocytes
本地全文：下载
作者：Jin-A Cho ; Eunha Oh ; Eunil Lee 等
期刊名称：Journal of Occupational Health
印刷版ISSN：1341-9145
电子版ISSN：1348-9585
出版年度：2003
卷号：45
期号：6
页码：376-381
DOI：10.1539/joh.45.376
出版社：Japan Society for Occupational Health
摘要：Comet assays were carried out to evaluate DNA damage in human lymphocytes from 20 volunteers before and after hair dyeing. DNA damage in lymphocytes was found to be slightly higher in volunteers after hair dyeing. Tail moments before and after hair dyeing were 1.47 ± 0.41 and 1.75 ± 0.29 respectively ( p <0.0008). DNA damage in lymphocytes showed significant difference with treatment and heating time. The tail moments after 15 min of treatment time before and after hair dyeing were 1.44 ± 0.22 and 1.85 ± 0.36, respectively ( p =0.0004) and the corresponding tail moments in 20 min of heating time before and after were 1.37 ± 0.15 and 1.78 ± 0.34 ( p =0.0002). In conclusion, we found that an acute exposure of hair dyes with heating caused DNA damages in peripheral lymphocytes and that this damage had significant association with treatment and heating time.
关键词：Comet assay;Lymphocytes;Hair;Dye