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标题：Factors Associated with Vitamin D Deficiency in European Adolescents: The HELENA Study
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作者：Jara VALTUEÑA ; Marcela GONZÁLEZ-GROSS ; Inge HUYBRECHTS 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2013
卷号：59
期号：3
页码：161-171
DOI：10.3177/jnsv.59.161
出版社：Center for Academic Publications Japan
摘要：Evidence indicates low 25-hydroxyvitamin D [(25(OH)D] concentrations in European adolescents. Identification of potential determinants is therefore essential to guide public health initiatives aiming at optimizing vitamin D status across Europe. The aim of the study was to identify potential influencing factors of 25(OH)D concentrations in European adolescents aged 12.5 to 17.5 y, participating in the multi-centre cross-sectional Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study. A subset of 1,006 participants (46.8% males) was drawn from the main study. Measures of body composition, biochemical markers, socioeconomic status, dietary intake, physical activity, fitness, sleep time and vitamin D genetic polymorphism (rs1544410) were assessed. Stepwise multivariate linear regression analysis was conducted stratified by gender. In males, linear regression of 25(OH)D, suggested that (1) winter season (β=−0.364; p <0.01), (2) higher latitudes (β=−0.246; p <0.01), (3) BMI z-score (β=−0.198; p <0.05) and (4) retinol concentration (β=0.171; p <0.05) independently influenced 25(OH)D concentrations. In females, (1) winter season (β=−0.370; p <0.01), (2) sleep time (β=−0.231; p <0.01), (3) supplement intake (β=0.221; p <0.05), (4) flexibility (β=0.184; p <0.05), (5) body fat % (β=0.201; p <0.05) (6), BMI z-score (β=−0.272; p <0.05), (7) higher latitudes (β=−0.219; p <0.01) and (8) handgrip strength (β=0.206; p <0.05) independently influenced 25(OH)D concentrations. Season, latitude, fitness, adiposity, sleep time and micronutrient supplementation were highly related to 25(OH)D concentrations found in European adolescents.
关键词：25(OH)D concentrations;insufficiency;determinants;adolescence;Europe