文章基本信息

标题：Lactobacillus plantarum OLL2712 Regulates Glucose Metabolism in C57BL/6 Mice Fed a High-Fat Diet
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作者：Tohru SAKAI ; Tomoyo TAKI ; Akiko NAKAMOTO 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2013
卷号：59
期号：2
页码：144-147
DOI：10.3177/jnsv.59.144
出版社：Center for Academic Publications Japan
摘要：The aim of the present study was to determine the effect of oral administration of Lactobacillus plantarum OLL2712 ( L. plantarum OLL2712) on glucose and lipid metabolism in mice with high-fat diet-induced obesity. Mice that had been administered 10⁹ cfu heat-killed L. plantarum OLL2712 for 12 wk showed significant reduction of blood glucose levels in response to insulin. Furthermore, mRNA expression of interleukin-1β in adipose tissue and serum levels of nonesterified fatty acids in mice administered L. plantarum OLL2712 were significantly lower than those in control mice. These results indicate that L. plantarum OLL2712 regulates glucose metabolism.
关键词：Lactobacillus plantarum;obesity;inflammation;adipose tissue