文章基本信息

标题：Improvement Effect of Resistant Maltodextrin in Humans with Metabolic Syndrome by Continuous Administration
本地全文：下载
作者：Chieko HASHIZUME ; Yuka KISHIMOTO ; Sumiko KANAHORI 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2012
卷号：58
期号：6
页码：423-430
DOI：10.3177/jnsv.58.423
出版社：Center for Academic Publications Japan
摘要：Resistant maltodextrin (RMD) is a soluble dietary fiber ingredient whose physiological functions are well recognized in Foods for Specified Health Use (FOSHU) for maintaining healthy intestinal regularity, blood glucose levels, and serum lipids. However, its efficacy on combined health risks—metabolic syndrome—was not studied yet. In this study the efficacy of RMD on humans with metabolic syndrome was investigated. A randomized double-blind placebo-controlled parallel-group trial was conducted. Thirty subjects with metabolic syndrome were randomly allocated into 2 groups and took either tea containing 9 g of RMD (treatment group) or placebo tea at three mealtimes daily for 12 wk. Blood was collected and body fat was scanned periodically. In the RMD treatment group, waist circumference, visceral fat area, fasting blood glucose, HOMA-R and serum triacylglycerol (TG) were significantly decreased compared to baseline, and significant time-by-treatment interaction was observed for waist circumference, visceral fat area, HOMA-R and serum TG ( p =0.044, p =0.012, p =0.032, and p =0.049, respectively). The change ratio of visceral fat area showed negative statistical correlation with the baseline value ( p =0.033), suggesting that efficacy of RMD was emphasized in the subjects having a larger visceral fat area. After the 12-wk RMD treatment, the total number of metabolic syndrome risk factors decreased to 20 from 32 with 2 subjects having no risks, while that of the placebo group decreased to 25 from 32. These findings suggest that continuous ingestion of RMD may improve the risk factors of metabolic syndrome by reducing visceral fat and improving glucose and lipid metabolism.
关键词：resistant maltodextrin;soluble dietary fiber;metabolic syndrome;glucose and lipid metabolism;visceral fat