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标题：Recovery and Maintenance of Copper Levels in Geriatric Patients on Enteral Feeding for a Prolonged Period
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作者：Yuki ITO ; Tetsuo ANDO ; Toshitaka NABESHIMA 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2006
卷号：52
期号：3
页码：200-204
DOI：10.3177/jnsv.52.200
出版社：Center for Academic Publications Japan
摘要：Latent copper deficiency develops after 3 mo in patients receiving enteral feeding solutions with low copper levels. We examined whether a copper-rich enteral solution restores and maintains the level of copper in serum for a prolonged period. The study group consisted of 13 patients (eight males and five females). Commercial preparations, F2α^® and Lifelon-PZ^®, for enteral administration were used. F2α^® and Lifelon-PZ^® contain 1.6 and 0.13 mg/L, respectively, of copper. Serum copper levels were monitored in patients before and after administration of F2α^®, a copper-rich enteral solution, at the neurological ward of Nagoya Daini Red Cross Hospital. Four of the 13 patients received Liflon-PZ^®, a copper-poor enteral solution, before this trial. Blood samples were taken every month. The daily average copper dosage with F2α^® was 1.8±0.4 mg/d (1.0-2.4 mg/d). The copper level in the four patients who received Liflon-PZ^® was 10.5±5.5 μmol/L before this trial. The level rose to 18.9±3.6 μmol/L 1 mo after the change to the copper-rich, F2α^®. The average serum copper level in the other patients before the start of enteral feeding was 15.3±5.0 μmol/L. The proper copper level was maintained with F2α^® in the long term. A copper-rich enteral preparation could easily restore and maintain serum copper levels for a prolonged period. A dose of 1.8±0.4 mg copper/d (1.0-2.4 mg/d) was sufficient for our patients.
关键词：copper;enteral nutrition;deficiency;nutritional assessment;dietary intake