文章基本信息

标题：Immunotherapy approaches for hematological cancers
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作者：Olivia L. Lanier ; Edgar Pérez-Herrero ; Abielle P. D.’ Andrea 等
期刊名称：iScience
印刷版ISSN：2589-0042
出版年度：2022
卷号：25
期号：11
页码：1-38
DOI：10.1016/j.isci.2022.105326
语种：English
出版社：Elsevier
摘要：SummaryHematological cancers such as leukemia, lymphoma, and multiple myeloma have traditionally been treated with chemo and radiotherapy approaches. Introduction of immunotherapies for treatment of these diseases has led to patient remissions that would not have been possible with traditional approaches. In this critical review we identify main disease characteristics, symptoms, and current treatment options. Five common immunotherapies, namely checkpoint inhibitors, vaccines, cell-based therapies, antibodies, and oncolytic viruses, are described, and their applications in hematological cancers are critically discussed.Graphical abstractDisplay OmittedHealth sciences; Immunology; Oncology; Biological sciences; Cancer