文章基本信息

标题：Multiple high-regional-incidence cardiac disease diagnosis with deep learning and its potential to elevate cardiologist performance
本地全文：下载
作者：Yunqing Liu ; Chengjin Qin ; Chengliang Liu 等
期刊名称：iScience
印刷版ISSN：2589-0042
出版年度：2022
卷号：25
期号：11
页码：1-17
DOI：10.1016/j.isci.2022.105434
语种：English
出版社：Elsevier
摘要：SummaryCurrently, due to lack of large-scale datasets containing multiple arrhythmias and acute coronary syndrome-related diseases, AI-aided diagnosis for cardiac diseases is limited in clinical scenarios. Whether AI-based ECG diagnosis can assist cardiologists to improve performance has not been reported. We constructed a large-scale dataset containing multiple high-regional-incidence arrhythmias and ACS-related diseases, including 162,622 12-lead ECGs collected between January 2018 and March 2021. We presented a deep learning model for clinical ECG diagnosis of multiple cardiac diseases. Results show that our model for diagnosing 15 cardiac abnormalities achieved 88.216% accuracy, and its average AUC ROC score reached 0.961. On the board-certified re-annotated dataset, its performance surpasses that of cardiologists in non-reference group. Moreover, with aid of labels given by our model, accuracy and efficiency for cardiologist increased by 13.5% and 69.9% than non-reference group. Our approach provides solutions for AI-aided diagnosis systems of cardiac diseases in applications.Graphical abstractDisplay OmittedHighlights•A large-scale clinical dataset containing multiple cardiac diseases is constructed•The performance of our DL model surpasses that of medical cardiologists•Cardiologists with DL results as reference can improve diagnostic performance•Our approach provides solutions for the future AI-aided diagnosis clinical systemCardiovascular medicine; Diagnostics; Biological sciences