文章基本信息

标题：Interaction of night shift work with polymorphism in melatonin receptor 1B gene on incident stroke
本地全文：下载
作者：Chen Y ; Yang L ; Liang YY 等
期刊名称：Scandinavian journal of Work, Environment and Health
印刷版ISSN：0355-3140
出版年度：2022
卷号：48
期号：5
页码：372-379
DOI：10.5271/sjweh.4025
语种：English
出版社：National Board of Occupational Safety and Health
摘要：This study showed that night shift work interacted with MTNR1B rs10830963 in predisposing to stroke. Particularly, the individuals with the CC genotype suffered a more pronounced risk of incident stroke when exposed to night shift work. Our findings extended the current knowledge about circadian biology in stroke and suggested a need to consider personalized circadian factors in stroke prevention.
关键词：circadian rhythm;incident stroke;melatonin;melatonin receptor 1B gene;MTNR1B rs10830963;nigh shift;polymorphism;stroke;UK Biobank