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  • 标题:MRP5b/SMRP mRNA is Highly Expressed in Metallothionein- Deficient Mouse Liver
  • 作者:Toshihiro Suzuki ; Mika Agui ; Tadayasu Togawa
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:2003
  • 卷号:49
  • 期号:6
  • 页码:524-526
  • DOI:10.1248/jhs.49.524
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:To investigate whether multidrug resistance protein 5 (MRP5) functions as a xenobiotic detoxification factor, we measured MRP mRNA expression levels in metallothionein (MT)-I, II knockout mouse, and the results showed that MRP5b/SMRP, a splicing variant of MRP5, was highly expressed in the liver of MT-I, -II null mice.
  • 关键词:metallothionein;multidrug resistance protein;multidrug resistance protein 5
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