文章基本信息

标题：Effect of Low-Dose Human Interferon-alpha on Shipping Fever of Thoroughbred Racehorses
本地全文：下载
作者：Makoto AKAI ; Seiji HOBO ; Shinya WADA 等
期刊名称：Journal of Equine Science
印刷版ISSN：1340-3516
电子版ISSN：1347-7501
出版年度：2008
卷号：19
期号：4
页码：91-91
DOI：10.1294/jes.19.91
出版社：Japanese Society of Equine Science
摘要：To assess the effect of human interferon-alpha (IFNα) on shipping fever of Thoroughbred racehorses subjected to long-distance transportation, an IFNα preparation was orally administered to 48 horses three times (once daily, 3 successive days) before transportation (IFNα group). In the control group (25 horses), maltose was administered in the same way. These treatments induced no abnormal findings in Thoroughbred racehorses before transportation. Immediately after transportation, significant increases in rectal temperature were observed in both treatment groups, whereas the rectal temperature of the IFNα group tended to be lower than that of the control group. Although WBC, Fbg, and SAA immediately after transportation were significantly increased due to transportation in both groups, the extent of the increases in the IFNα group was significantly smaller than in the control group. Long-distance transportation had a relatively profound impact on Thoroughbred racehorses, which was mitigated by IFNα treatment.
关键词：human interferon-alpha;low-dose;oral administration;thoroughbred racehorses;shipping fever