文章基本信息

标题：Effects of Exercise on Plasma Haptoglobin Composition in Control and Splenectomized Thoroughbred Horses
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作者：Kei HANZAWA ; Atsushi HIRAGA ; Yutaka YOSHIDA 等
期刊名称：Journal of Equine Science
印刷版ISSN：1340-3516
电子版ISSN：1347-7501
出版年度：2002
卷号：13
期号：3
页码：89-92
DOI：10.1294/jes.13.89
出版社：Japanese Society of Equine Science
摘要：In splenectomized Thoroughbred horses ( Group S ), the plasma haptoglobin ( Hp ) concentration was increased by the operation but thereafter significantly decreased to a lower level than before the surgery. The red cell haemolysis rate in a hypotonic salt solution and haemoglobin ( Hb ) binding Hp after exercise in Group S were significantly lower than in control horses ( Group C ). These results suggest that: 1) the spleen accelerates the fragility of the red cell membrane; 2) osmotic sensitive red cells are easy to haemolyze during exercise; and 3) the haemolysis during exercise increases the Hb-binding Hp level in plasma and then accelerates the synthesis of Hp in liver. Therefore, plasma Hp is a clinical indicator of red cell membrane fragility and haemolysis in a blood vessel during exercise.
关键词：exercise;haptoglobin;horse;osmotic fragility;red cells