文章基本信息

标题：Determination and Variability of Nucleotide Sequences for D4 Dopamine Receptor Genes (DRD4) in Genus Equus
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作者：Telhisa HASEGAWA ; Fumio SATO ; Nobushige ISHIDA 等
期刊名称：Journal of Equine Science
印刷版ISSN：1340-3516
电子版ISSN：1347-7501
出版年度：2002
卷号：13
期号：2
页码：57-62
DOI：10.1294/jes.13.57
出版社：Japanese Society of Equine Science
摘要：The D4 dopamine receptor gene (DRD4) polymorphic region, which is possibly related to the personality trait known as Novelty Seeking in humans, was examined in equids. Partial nucleotide sequences in exon 3 of DRD4 gene were compared among several species in genus Equus. Inter-and intra-species differences were observed, as well as between two domestic horse breeds, Thoroughbred and Kiso pony (Japanese native pony). In equids, these variations were consisted of as many as 9 fold repeats of 18 bp variable number of tandem repeat (VNTR) type polymorphisms and single nucleotide polymorphisms (SNPs).
关键词：D4 dopamine receptor;genus Equus;polymorphisms