文章基本信息

标题：Impact of Lifestyle on Overall Cancer Risk among Japanese: The Japan Public Health Center-Based Prospective Study (JPHC Study)
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作者：Manami Inoue
期刊名称：Journal of Epidemiology
印刷版ISSN：0917-5040
电子版ISSN：1349-9092
出版年度：2010
卷号：20
期号：2
页码：90-96
DOI：10.2188/jea.JE20090209
出版社：Japan Epidemiological Association
摘要：In Japan, cancer has long been recognized as a major component of the overall pattern of disease. Currently, there is a need to implement practical control measures with specific numerical targets appropriate for the Japanese population. Using data from the Japan Public Health Center-based Prospective Study, the author estimated the impact of major risk factors on overall cancer risk among a Japanese population. These risk factors included tobacco smoking, alcohol drinking, body mass index, history of diabetes, physical activity, and metabolic factors and their aggregates. The results show that tobacco smoking and heavy alcohol drinking were significantly positively associated with overall cancer risk, and that total physical activity was significantly inversely associated with the risk of cancer. Although people with a history of diabetes may be at increased risk of cancer, extreme body mass index and metabolic factors in the aggregate had little impact on overall cancer risk in the Japanese population.
关键词：cancer;risk factor;attributable fraction;Japanese;cohort study