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标题：Green synthesis and pharmacological applications of silver nanoparticles using ethanolic extract of Salacia chinensis L.
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作者：Madhuranthakam Reddi Nagesh ; Nirubama Kumar ; Javed Masood Khan 等
期刊名称：Journal of King Saud University - Science
印刷版ISSN：1018-3647
出版年度：2022
卷号：34
期号：7
页码：1-9
DOI：10.1016/j.jksus.2022.102284
语种：English
出版社：Elsevier
摘要：Graphical abstractDisplay OmittedAbstractObjectivesIn recent years, biological precursor-based synthesis, particularly plant-based green synthesis, has piqued attention in the area of nanotechnology. The goal of this work is to look into the antibacterial, antifungal, antioxidant, and antiproliferation activity of silver nanoparticles (AgNPs) made from ethanolic extract ofSalacia chinensisL. were investigated.MethodsThis study can be broadly separated into three parts: the first extraction fromSalacia chinensisL. roots, The second characterization of NPs by UV-Vis, DLS, FTIR and SEM, and the third analysis of its antimicrobial; antioxidant and antiproliferative properties. UV–Vis absorption indicated the synthesis of AgNPs, and the spectrum was seen at 401 and 447 nm. The existence of functional groups in the produced AgNPs was verified by FT-IR spectral peaks at 3423.83 cm−1. In three planes, XRD was calculated to investigate the crystallinity and consistent spherical size (peaks at 2θ values of at 28.78, 32.18, 38.04, 54.63, and 77.08°) of the particles.ResultsThe results of antibacterial, antifungal and antiproliferative effect of synthesized AgNPs withSalacia chinensisL. ethanolic root extract have admirable antimicrobial (19.5 mm), antioxidant (IC50values 117.3, 59.61 g mL−1) and antiproliferative activity against HEK293 cell lines protect up to 90.3 % respectively.ConclusionsAs a consequence, biosynthesizedSalacia chinensisL. AgNPs shown outstanding effects and have the potential to be used as antibacterial, antioxidant, and antiproliferative agents.
关键词：KeywordsSilver nanoparticlesSalacia chinensis LAntimicrobialAntiproliferationHEK293 cell lines