文章基本信息

标题：Healing Properties of Some Indian Medicinal Plants against Indomethacin-Induced Gastric Ulceration of Rats
本地全文：下载
作者：Sayanti Bhattacharya ; Susri R. Chaudhuri ; Subrata Chattopadhyay 等
期刊名称：Journal of Clinical Biochemistry and Nutrition
印刷版ISSN：0912-0009
电子版ISSN：1880-5086
出版年度：2007
卷号：41
期号：2
页码：106-114
DOI：10.3164/jcbn.2007015
出版社：The Society for Free Radical Research Japan
摘要：The healing activity of the ethanol extracts of Piper betel , Emblica officinalis , Terminalia bellerica , and Terminalia chebula against the indomethacin-induced stomach ulceration has been studied and compared with that of misoprostol. Compared to autohealing, all the drugs accelerated the healing process, albeit to different extents. The relative healing activities of the extracts was P. betel > E. officinalis > T. bellerica ~ T. chebula , that correlated well with their in vivo antioxidant and mucin augmenting activities. The excellent healing activity of the extracts of P. betel and E. officinalis indicated a major role of mucin protection and regeneration in the healing of nonsteroidal anti-inflammatory drugs mediated stomach ulceration.
关键词：antioxidant;Indian medicinal plants;indomethacin;mucin;stomach ulcer