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标题：Quality of Life and Associated Factors in Patients Infected with Hepatitis B and C Virus in a Moroccan Region: A Cross-Sectional Study
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作者：Diagne Bineta Jho ; Abid Hakima ; Ibtissam El Harch 等
期刊名称：Open Access Library Journal
印刷版ISSN：2333-9705
电子版ISSN：2333-9721
出版年度：2022
卷号：9
期号：5
页码：1-13
DOI：10.4236/oalib.1108781
语种：English
出版社：Scientific Research Pub
摘要：Introduction: Hepatitis B or C virus infection is one of the most common liver infections leading to altered health-related quality of life (HRQoL) in patients. The goal of this study was to assess the quality of life of patients infected with hepatitis B or C virus and to determine the factors that might be associated with worse outcomes. Methods: A cross-sectional study was conducted in patients aged 18 years and over followed on an outpatient basis at the teaching hospital Hassan II in Fez for hepatitis B or C. These patients were asked to complete the SF-12 questionnaire file which is the short form of the quality measurement scale of life SF-36. Sociodemographic, clinical and economic information was collected. A descriptive analysis was carried out, then a univariate analysis in search of factors associated with quality of life, and finally a multivariate analysis by linear regression was carried out adjusting for possible confounding factors. Results: A total of 94 patients whose mean age was 55.69 ± 13.25 years met the inclusion criteria. The physical quality of life was altered with an average of 41.98 ± 12.67. Hepatitis C virus infection (β = -6.802; 95% CI = (-12.05; -1.55)), cirrhosis (β = -6.947, 95% CI = (-12.04; -1.84)) and lack of employment (β = -8.48, 95% CI = (-13.18; -3.77)) were the factors associated with poor quality of life. The mental quality of life (MCS) was also altered with an average of 46.32 ± 12.84. In multivariate analysis we found that participants with hepatitis C (β = 7.444, 95% CI = (2.14; 12.74)), unemployed (β = 6.697, 95% CI (2.28; 11.11)) and having received treatment (β = 8.295, 95% CI (2.95; 13.63) had a better mental quality of life, while alcoholics had an impaired mental quality of life (β = -8.105, 95% CI (-15.28; -0.92)). Conclusion: Quality of life is altered in patients with chronic hepatitis regardless of type.
关键词：Quality of LifeChronic HepatitisHepatitis B VirusHepatitis C VirusSF12Health-Related Quality of LifeMorocco