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标题：Risk Factors Associated With The Prolonged Usage Of Inhaled Corticosteroids In Case Of Asthma, Copd And Acos Cases Compared With The Controls
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作者：Bala Maheswari kommineni ; Gunapriya Raghunath ; Asha latha 等
期刊名称：Webology
印刷版ISSN：1735-188X
出版年度：2022
卷号：19
期号：2
页码：6869-6880
语种：English
出版社：University of Tehran
摘要：INTRODUCTION: The effect of Inhaled corticosteroid therapy may vary in COPD, ACOS and asthmatic cases. The influence of risk factors like age, BMI, stress BP and fracture history are adding to the adverse effects of inhaled corticosteroids. This study aims to assess the risk associated with the prolonged use of inhaled corticosteroids in case of Asthma, COPD, and ACOS compared with the controls. reduced bone mineral density that leads to fracture risk and also to assess bone mineral density, vitamin D, and BMI. MATERIAL AND METHODS: A total of 259 patients were involved in this cross-sectional study, 122 males and 137 females along with the controls. The study was conducted at the NRI Institute of Medical Sciences after getting the ethical committee clearance and received consent form from each subject along with their accompanied ones. 30 cases with serum micro RNA 146 compared with 10 controls RESULTS: Cases were identified with osteoporosis and osteopenia in both females and males. The subjects who got low BMD also have low BMI. CONCLUSION: The major risk factors like age, BMI, occupational stress are not in our hands, only solution that, management by decreased usage of inhaled corticosteroids. that is only in certain COPD cases with the minority of patients in whom the treatment works better rather than the adverse effects. In asthma and ACOS cases life style changes with dietary management improves the situation.
关键词：inhaled corticosteroids;risk factors;asthma;COPD;ACOS