文章基本信息

标题：Evaluation of transdermal exposure of phthalates in children's product
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作者：Jihye Hwang ; Young-Wook Lim ; Ji-Yeon Yang 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：2022
卷号：37
DOI：10.5620/eaht.2022005
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：In this study, 16 children’s products with the highest detection potential of phthalates were selected, and a phthalate assay and transdermal delivery analysis (NIER, US EPA Wipe [stress condition], US EPA Wipe [physiological condition], and US EPA Hand Wipe) were conducted with these products. The content of 6 controlled phthalates (DBP, BBP, DEHP, DNOP, DINP, and DIDP) was measured and most products contained more phthalates than the regulated guidelines (a total content of 6 phthalates to be ≤0.1%). For transdermal delivery, all items were found to be lower in the NIER transdermal delivery test method compared to the US EPA Hand Wipe (stress condition and physiological condition) transdermal delivery test method. For the US EPA Hand Wipe (stress condition and physiological condition) transdermal delivery test method, a similar result was observed, except for DINP. The average daily dose (ADD) estimated by determining the exposure algorithm for each transdermal delivery test method was highest in mats with a large contacting surface area and a long exposure time in the respective test methods. Conclusively, there was a difference between the NIER transdermal delivery test method and the US EPA Wipe transdermal delivery test method.
关键词：children’s products;phthalates;transdermal delivery amount;ADD.