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标题：Risk of Herpes Zoster in Relation to Body Mass Index Among Residents Aged ≥50 Years: The Shozu Herpes Zoster Study
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作者：Kazuhiro Kawahira ; Hironori Imano ; Keiko Yamada 等
期刊名称：Journal of Epidemiology
印刷版ISSN：0917-5040
电子版ISSN：1349-9092
出版年度：2022
卷号：32
期号：8
页码：370-375
DOI：10.2188/jea.JE20200473
语种：English
出版社：Japan Epidemiological Association
摘要：Background The impact of body mass index on incidence of herpes zoster is unclear. This study investigated whether body mass index was associated with a history of herpes zoster and incidence during a 3-year follow-up, using data from a prospective cohort study in Japan. Methods In total, 12,311 individuals were included in the cross-sectional analysis at baseline, of whom 1,818 with a history of herpes zoster were excluded from the incidence analysis, leaving 10,493 individuals. Body mass index (kg/m 2) was classified into three categories (underweight: <18.5; normal: 18.5 to <25; and overweight: ≥25). To evaluate the risk of herpes zoster, we used a logistic regression model for prevalence and a Cox proportional hazard regression model for incidence. Results Being overweight or underweight was not associated with herpes zoster prevalence at baseline. The multivariate hazard ratios of herpes zoster incidence for overweight versus normal-weight groups were 0.67 (95% confidence interval, 0.51–0.90) in all participants, and 0.57 (95% confidence interval, 0.39–0.83) in women, with no significant difference for men. Conclusion Being overweight was associated with a lower incidence of herpes zoster than being normal weight in older Japanese women.
关键词：Key words:enherpes zosterbody mass indexoverweightcohort study