文章基本信息

标题：Role of Methotrexate in Management of Generalized Psoriasis
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作者：Samar Mohamed Abdelaziz Elsedawy ; Mohamed Ibrahim Metwalli ; Manal Mohamed Fawzy 等
期刊名称：International Journal of Early Childhood Special Education
电子版ISSN：1308-5581
出版年度：2022
卷号：14
期号：2
页码：1255-1260
DOI：10.9756/INT-JECSE/V14I2.109
语种：English
出版社：International Journal of Early Childhood Special Education
摘要：Psoriasis is a chronic inflammatory skin disease with a complex aetiopathogenesis. Several factors could contribute to psoriasis pathogenesis, including genetic, environmental, and immune-mediated factors. Several clinical variants of psoriasis have been identified, with plaque-type psoriasis being the most common variant.Methotrexate (MTX), a classic anti-psoriatic drug, is still very useful either as single-drug therapy or in combination with other systemic drugs, particularly as a rescue therapy or when combined with biologics. It is widely used internationally as an initial therapy for the treatment of psoriasis and psoriatic arthritis.
关键词：Methotrexate;Generalized Psoriasis