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标题：Centellaasiatica aqueous extract preparation and its antifungal activity against Candida albicans
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作者：Ngoubinah pretty TM ; Rajeshkumar ; Gheena.S 等
期刊名称：International Journal of Early Childhood Special Education
电子版ISSN：1308-5581
出版年度：2022
卷号：14
期号：2
页码：3077-3082
DOI：10.9756/INT-JECSE/V14I2.304
语种：English
出版社：International Journal of Early Childhood Special Education
摘要：Introduction: Centellaasiatica belong to a family Apiaceae is a common perennial herbaceous creeper flourishing abundantly in moist areas and distributing widely in tropical and subtropical countries, various chemicals constituents are reported in Centellaasiaticalike asiaticoside,madecassoside, madecassicacid,asiatic acid. Materials and method: Three grams of dry powder of centellaasiatica powder were weighed and taken,which was commercially available in powder form and therefore it was easy to purchase. 200ml of distilled water was added. Then the mixture was boiled and centrifuged at 8000 rpm for 10 minutes. The extract was then placed in the well cultured agar plates (rose bengal agar) against Candida albicans and incubated for 24 hours at 37ºC. Result: In the nanoparticles the result shows 25μl of concentration with 9mm of zone of inhibition, 50μl of concentration with 9mm of zone of inhibition, 100μl of concentration with 10mm of zone of inhibition, and zone of inhibition for antibiotic was 11mm Conclusion: In this study the aim was to find antifungal activity in centellaasiatica in C.albicans and we found that Centellaasiatica mediated in aqueous extraction showed us wider zones of inhibition of good antifungal efficiency.
关键词：Centellaasiatica;Natural;antioxidant;antifungal;extract;innovative technique;green synthesis